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| Set | Card | | Card Description | |
| 1967 Topps | 70 | | Santo, Ron (Chicago Cubs ) |
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| 1968 Topps | 5 | | NL HR Leaders Aaron, Hank (Atlanta Braves ) LL McCovey, Willie (San Francisco Giants) LL Santo, Ron (Chicago Cubs ) LL Wynn, Jimmy (Houston Astros ) LL |
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| 1968 Topps | 235 | | Santo, Ron (Chicago Cubs ) |
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| 1968 Topps | 366 | | Santo, Ron (Chicago Cubs ) AS |
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| 1969 Topps | 4 | | NL RBI Leaders McCovey, Willie (San Francisco Giants) LL Santo, Ron (Chicago Cubs ) LL Williams, Billy (Chicago Cubs ) LL |
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| 1969 Topps | 420 | | Santo, Ron (Chicago Cubs ) AS |
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| 1969 Topps | 570 | | Santo, Ron (Chicago Cubs ) |
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| 1970 Topps | 63 | | NL RBI Leaders McCovey, Willie (San Francisco Giants) LL Perez, Tony (Cincinnati Reds) LL Santo, Ron (Chicago Cubs ) LL |
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| 1970 Topps | 454 | | Santo, Ron (Chicago Cubs ) AS |
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| 1970 Topps | 670 | | Santo, Ron (Chicago Cubs ) |
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| 1971 Topps | 220 | | Santo, Ron (Chicago Cubs ) |
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| 1972 Topps | 555 | | Santo, Ron (Chicago Cubs ) |
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| 1972 Topps | 556 | | Santo, Ron (Chicago Cubs ) IA |
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| 1973 Topps | 115 | | Santo, Ron (Chicago Cubs ) |
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| 1974 Topps | 270 | | Santo, Ron (Chicago Cubs ) |
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| 1974 Topps Traded | 270 | T | Santo, Ron (Chicago Cubs ) |
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| 1974 Topps | 334 | | All-Star Third Basemen Robinson, Brooks (Baltimore Orioles) AS Santo, Ron (Chicago Cubs ) AS |
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| 1975 Topps | 35 | | Santo, Ron (Chicago White Sox) |
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